A Syringe Filter is also called a wheel filter due to its wheel-like shape. It is a single-use membrane-based filter cartridge for attachment with a syringe to remove any impurities in the liquid solutions. This step is essential for preventing damage to instruments such as liquid chromatography and ICP. These disposable syringe filters, are used in medical labs for quick and efficient filtering. They are suitable for material purification and sterilization for solutions less than 250mL.
Choose the appropriate syringe filter, ensuring proper testing results and correct purifying performance. Consideration of membrane diameters, materials, and pore size is important. Here, you will get insights on the essential factors for helping you make the right choice.
Insights on PVDF (Hydrophilic) Syringe Filter Selection
Here we will discuss about selection criteria for the PVDF Syringe Filters in detail:
Which Syringe Filter Diameter?
Filter inlets are female Luer-Lock compatible and come in three diameters. The diameter of the filter inlets is determined by the volume required for filtration.
13 mm Syringe Filters
· For sample volumes that are less than 10 mL.
· It is a convenientand appropriate choice for most applications.
· Holdup volume is less than 15 ul.
· It consists of the female inlet luer lock
· The maximum operation pressure is less than 15 bar
25 mm Syringe Filters
· For sample volumes that are less than the 100 mL range;
· Holdup or dead volume is less than 125 ul.
· It has a Female inlet luer lock
· The maximum operation pressure less than 10 bar
33 mm filters
· For sample volumes less than 250 mL range;
· Holdup or dead volume is less than 180 ul.
· Having female inlet luer lock
· 33mm filters are best suited for high throughput labs
Pore Sizes: 0.22um or 0.45um?
The commonly used syringe filter pore sizes are 0.2/0.22 um and 0.45 um.
1. The pore size used is necessary for determining the particle size for elimination. So, to filter out particulate matter greater than 0.2 microns in diameter, consider choosing a syringe filter with a 0.2-micron pore size.
2. For determining the micron size of columns, 0.45 um for greater3 um, and 0.22 um for less than 3 um.
3. 0.45 um membranes are gererally used for filtration and particle removal, while 0.2/0.22um sterilizing-grade membranes are used for solution sterilization.
Which one is the most suitable – Sterile or Non-Sterile?
The filters, are used to eliminate unwanted particles from a solution. The selection of sterile or non-sterile is dependent on the processing applications:
· For the requirement of sterilized solution, sterile syringe filters are available and are wrapped to ensure optimal performance without contamination.
· For a solution required to be filtered through a sterilization process, a non-sterile syringe filter can be suitable.
Conclusion
The PVDF Syringe Filters are suitable for biological filtration. These filters are specially designed for applications where there is the necessity of high protein recovery. PVDF (Hydrophilic) Syringe Filters do not need prior wetting with alcohol for aqueous samples.When searching for syringe filters like Nylon Syringe Filter, you can contact Simsii, inc., a leader in providing Syringe filter services. These filters provide much cleaner sample extracts by removing unwanted materials and fine particles. A syringe filtration step before chromatographic injection helps ensure more consistent and dependable results. It also helps to protect instruments and enhance their life. Syringe Filters are available in variety-of sizes and membrane types suitable for different application needs.